hrp0097fc7.4 | Sex differentiation, gonads and gynaecology or sex endocrinology | ESPE2023

The effect of common genetic variants in CYP19A1 on serum Estradiol to Testosterone Ratio in healthy Danish children and adolescents

L. R. Groendahl Veronica , A. Holmboe Stine , S. Busch Alexander , Aksglaede Lise , P. Hagen Casper , H. Johannsen Trine , H. Petersen Jørgen , Almstrup Kristian , Frederiksen Hanne , Juul Anders

Background and Aim: Despite the broad individual variation of pubertal maturation, references traditionally describe growth in relation to just chronological age and not biological age. Hence, growth references for the adolescent period have been of limited usefulness for monitoring individual growth in clinic and for research. Especially for children and adolescents with chronic diseases is there a need to better evaluate if changes in SD-scores just before a...